Accumulation of DNA methylation alterations in paediatric glioma stem cells following fractionated dose irradiation.

Anna DanielssonKristell BarreauTeresia KlingMagnus TisellHelena Carén

Published in: Clinical epigenetics (2020)

DNA methylation alterations of sites with regulatory functions in proliferation and differentiation were identified, which may reflect cellular response to radiation stress through epigenetic reprogramming and differentiation cues.

Keyphrases

dna methylation
stem cells
genome wide
gene expression
intensive care unit
signaling pathway
transcription factor
copy number
cell therapy
small cell lung cancer
bone marrow