Left atrial strain in patients with β-thalassemia major: a cross-sectional CMR study.
Antonella MeloniLuca SabaVincenzo PositanoLaura PistoiaMichele PorcuFrancesco MasseiPaola Maria Grazia SannaFilomena LongoPiera GiovangrossiCrocetta ArgentoCalogera GerardiFilippo CademartiriRiccardo CauPublished in: European radiology (2024)
• Compared to healthy subjects, β-thalassemia major patients demonstrated significantly lower left atrial reservoir strain and booster strains, as well as left atrial reservoir and booster strain rates. • In β-thalassemia major, ageing, sex, and left ventricular volume indexes were independent determinants of left atrial strain parameters, while left atrial strain parameters were not correlated with myocardial iron overload. • An independent association between reduced left atrial strain parameters and a history of cardiac complications was found in β-thalassemia major patients.
Keyphrases
- left atrial
- left ventricular
- mitral valve
- atrial fibrillation
- catheter ablation
- end stage renal disease
- hypertrophic cardiomyopathy
- heart failure
- cardiac resynchronization therapy
- newly diagnosed
- chronic kidney disease
- acute myocardial infarction
- ejection fraction
- aortic stenosis
- sickle cell disease
- prognostic factors
- patient reported outcomes
- transcatheter aortic valve replacement
- acute coronary syndrome
- water quality