Aberrant brain structural large-scale connectome in Crohn's disease.

Anne Kerstin ThomannWolfgang ReindlTorsten WüstenbergDagny KmucheMatthias P EbertKristina SzaboRobert Christian WolfDusan HirjakBeate NieslerMartin GriebePhilipp A Thomann

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)

These findings lend support to the hypothesis that CD is accompanied by alterations in both global network organization and regional connectivity. A deeper understanding of neural central networks in IBD may facilitate the development of complementary strategies in the treatment of "extraintestinal" comorbid conditions such as depression or anxiety.

Keyphrases

resting state
functional connectivity
white matter
sleep quality
depressive symptoms
multiple sclerosis
physical activity
smoking cessation