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Global transcriptomic analyses of Salmonella enterica in Iron-depleted and Iron-rich growth conditions.

Bijay K KhajanchiJoshua XuChristopher J GrimAndrea R OttesenPadmini RamachandranSteven L Foley
Published in: BMC genomics (2019)
Iron concentrations in growth media influenced differential gene expressions both at transcriptional and translational levels, including genes encoded on the IncFIB plasmid. Limited iron availability within the host may promote pathogenic Salmonella to differentially express subsets of genes encoded by chromosome and/or plasmids, facilitating establishment of successful infection.
Keyphrases
  • escherichia coli
  • genome wide
  • iron deficiency
  • genome wide identification
  • copy number
  • gene expression
  • transcription factor
  • crispr cas
  • rna seq
  • multidrug resistant
  • heat shock protein
  • listeria monocytogenes