Analytical Validation of a Telomerase Reverse Transcriptase (TERT) Promoter Mutation Assay.

Priyanka C IyerRamona DaduAnna BarqueCleslei ZanelliXingyu ZhengHuimin JiangP Sean WalshYangyang HaoJing HuangJoshua P Klopper Richard T KloosMaria Cabanillas

Published in: The Journal of clinical endocrinology and metabolism (2024)

The analytical robustness and reproducibility of the Afirma TERT test support its routine clinical use among thyroid nodules with indeterminate cytology that are Afirma Genomic Sequencing Classifier suspicious or among Bethesda V/VI nodules.

Keyphrases

fine needle aspiration
ultrasound guided
liquid chromatography
dna methylation
high throughput
single cell
gene expression
transcription factor
clinical practice
copy number
mass spectrometry