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Functional status and spatial architecture of tumor-infiltrating CD8+ T cells are associated with lymph node metastases in non-small cell lung cancer.

Guanqun YangSiqi CaiMengyu HuChaozhuo LiLiying YangWei ZhangJujie SunFenghao SunLigang XingXiaorong Sun
Published in: Journal of translational medicine (2023)
Tumor-infiltrating CD8 + T cells were in a more dysfunctional status and in a more immunosuppressive microenvironment in patients with LNM compared with those without LNM.
Keyphrases
  • lymph node
  • stem cells
  • neoadjuvant chemotherapy
  • early stage
  • locally advanced