A Greener and Efficient Method for Nucleophilic Aromatic Substitution of Nitrogen-Containing Fused Heterocycles.
Joana Filomena CamposMohammed LoubidiMarie-Christine ScherrmannSabine Berteina-RaboinPublished in: Molecules (Basel, Switzerland) (2018)
A simple and efficient methodology for the nucleophilic aromatic substitution of nitrogen-containing fused heterocycles with interesting biological activities has been developed in an environmentally sound manner using polyethylene glycol (PEG-400) as the solvent, leading to the expected compounds in excellent yields in only five minutes.
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