Evidence-Based Clinical Practice Guidelines on Regenerative Medicine Treatment for Chronic Pain: A Consensus Report from a Multispecialty Working Group.
Ryan Steven D'SouzaYeng F HerNasir HussainJay KarriMichael E SchatmanAaron K CalodneyChristopher M LamThomas BuchheitBrennan J BoettcherGeorge C Chang ChienScott G PritzlaffChristopher CentenoShane A ShapiroJohana KlasovaJay S GriderRyan HubbardEliana EgeShelby JohnsonMax H EpsteinEva KubrovaMohamed Ehab RamadanAlexandra Michelle MoreiraSwarnima VardhanYashar EshraghiSaba JavedNewaj M AbdullahPaul J ChristoSudhir DiwanLeslie C HassettDawood SayedTimothy Ray DeerPublished in: Journal of pain research (2024)
In well-selected individuals with certain chronic pain indications, use of injectable biologics may provide superior analgesia, functionality, and/or quality of life compared to conventional medical management or placebo. Future high-quality randomized clinical trials are warranted with implementation of minimum reporting standards, standardization of preparation protocols, investigation of dose-response associations, and comparative analysis between different injectable biologics.