System analysis based on the cancer-immunity cycle identifies ZNF207 as a novel immunotherapy target for hepatocellular carcinoma.
Xu WangTao ZhouXingyi ChenYu WangYushi DingHaoyang TuShengyang GaoHaoyu WangXinying TangYong YangPublished in: Journal for immunotherapy of cancer (2022)
Our study implicates ZNF207 in suppressing the HCC microenvironment and showed the feasibility of targeting ZNF207 during anti-PD1 therapy in HCC.