Changes in Hemodynamic Response Function Resulting From Chronic Alcohol Consumption.
John E DesmondLaura C RiceDominic T ChengJun HuaQin QinJessica J RileeMonica L FaulknerYi-Shin SheuJoanna R MathenaGary S WandMary E McCaulPublished in: Alcoholism, clinical and experimental research (2020)
These findings suggest that excessive alcohol consumption is associated with changes in the HRF undershoot. HRF changes could provide a possible biomarker for the effects of lifetime drinking on brain function. Changes in HRF topography affect fMRI activation measures, and subject-specific HRFs generally improve fMRI activation results.