Effect of topical berberine in murine cutaneous leishmaniasis lesions.
Alba CalvoEsther MorenoIrati AldalurCarmen SanmartínEsther LarreaElena González-PeñasJuan Manuel IracheSocorro EspuelasPublished in: The Journal of antimicrobial chemotherapy (2022)
The twice-a-day administration of a topical berberine cream was safe, able to stop parasite progression and improved the appearance of skin CL lesions. The relationship between drug plasma levels and in vivo effect was unclear.