Circulating Tumor Cells and Breast Cancer Metastasis: From Enumeration to Somatic Mutational Profile.
Chengjun ZhuJing XuJin-Yu SunShiyun CuiYue SunTao YuCenzhu WangTianyao WangYufeng WuFeng JuJia-Feng YaoKai LiuWenwen ZhangXiaoxiang GuanPublished in: Journal of clinical medicine (2022)
Our study revealed that CTCs ≥ 5 are a risk factor for tumor metastasis in breast cancer patients. In addition, we reported that CTCs ≥ 5 might be associated with a higher risk of liver metastasis in patients with metastatic breast cancer. We have provided the mutational profiles of CTCs based on next-generation sequencing.