Asparaginyl endopeptidase may promote liver sinusoidal endothelial cell angiogenesis via PI3K/Akt pathway.

Na Li Chu Liu Guifen Ma Yujen Tseng Duyi Pan Jie Chen Feng Li Xiaoqing Zeng Tiancheng Luo Shi-Yao Chen

Published in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (2020)

AEP promotes LSECs angiogenesis in vitro, possibly via the PI3K/Akt pathway. AEP may therefore be a potential therapeutic target for preventing the progression of liver fibrosis.

Keyphrases

endothelial cells
liver fibrosis
vascular endothelial growth factor
high glucose
wound healing