Low rate of COVID-19 pneumonia in kidney transplant recipients-A battle between infection and immune response?

Maryam Ghaffari Rahbar Mohsen Nafar Alireza Khoshdel Nooshin Dalili Alireza Abrishami Ahmad Firouzan Fatemeh Pour-Reza-Gholi Fariba Samadian Shadi Ziaie Somayeh Fatemizadeh Shiva Samavat

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2020)

Low rate of admission in transplant recipients specially in the very first years of transplantation might be due to protective effects of immunosuppressive agents against cytokine storm or modification of immunity function. We suggest evaluation of T-cell number, function, and cytokine profile as a guide to manage COVID-19 mainly in patients with higher risk of mortality.

Keyphrases

coronavirus disease
sars cov
immune response
emergency department
respiratory syndrome coronavirus
risk factors
dendritic cells
stem cells
toll like receptor
mesenchymal stem cells
intensive care unit
cell therapy
inflammatory response