An antimicrobial peptide with an aggregation-induced emission (AIE) luminogen for studying bacterial membrane interactions and antibacterial actions.

Ning Ning LiJun Zhi LiPeng LiuDicky PranantyoLei LuoJiu Cun ChenEn-Tang KangXue Feng HuChang Ming LiLi Qun Xu

Published in: Chemical communications (Cambridge, England) (2018)

A fluorescence technique to investigate the interactions between bacterial membranes and an aggregation-induced emission (AIE) luminogen-decorated AMP (TPE-AMP) was reported. Our simple and fast method consists of mixing TPE-AMP and bacterial suspensions and recording the fluorescence signals by flow cytometry and confocal microscopy in a "non-washing" manner.

Keyphrases

protein kinase
flow cytometry
single molecule
living cells
fluorescent probe
energy transfer
quantum dots
gold nanoparticles
wound healing