DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Marco La FortezzaGiovanna GrigolonAndrea CosoloAlexey PindyurinLaura BreimannHelmut BlumBas van SteenselAnne-Kathrin Classen

Published in: Epigenetics & chromatin (2018)

Our study opens avenues for robust profiling of small cell population in imaginal discs in vivo and provides insights into epigenetic changes underlying transcriptional responses to tumorigenic transformation.

Keyphrases

single cell
gene expression
dna methylation
cell therapy
stem cells
mesenchymal stem cells
oxidative stress
bone marrow
heat shock
heat shock protein