Managing pain and anxiety during transabdominal chorionic villus sampling. A noninferiority randomized trial of nitrous oxide vs local anesthesia.

Maria KatsogiannouXavier-Côme DonatoAnderson LoundouEric GlowaczowerMarie RaffrayBrigitte Planchet-BarraudEdwin QuarelloMarie-Pierre BrechardRaoul Desbriere

Published in: Acta obstetricia et gynecologica Scandinavica (2018)

N2 O was as efficient and even superior to local anesthesia for both pain and anxiety reduction during CVS, as the 95% confidence intervals were both below the prespecified noninferiority margin of 0.8 and below zero.

Keyphrases

chronic pain
pain management
neuropathic pain
sleep quality
spinal cord
physical activity
postoperative pain