Construction of circ_0071922-miR-15a-5p-mRNA network in intervertebral disc degeneration by RNA-sequencing.
Yongjin LiBaobao WangWenzhi SunChao KongJunzhe DingFeng HuJianhua LiXiaolong ChenShibao LuPublished in: JOR spine (2023)
The findings of this study suggested that circ_0071922-miR-15a-5p-mRNA signaling network might affect IVDD by modulating the nucleus pulposus cells ferroptosis, oxidative stress, ECM metabolism, and immune response, which is an effective therapeutic targets of IVDD.