Hemolymph of triatomines presents fungistatic activity against Cryptococcus neoformans and improves macrophage function through MCP-I/TNF-α increase.
Luísa Menezes-SilvaJonatas da Silva CatarinoLaura Caroline de FariaBárbara Cristina PizzolanteLeonardo Eurípedes Andrade-SilvaMarcos Vinicius da SilvaVirmondes RodriguesHelioswilton Sales-CamposCarlo José Freire de OliveiraPublished in: The journal of venomous animals and toxins including tropical diseases (2022)
These results suggested that hemolymph of triatomines may represent a source of molecules capable of presenting antifungal and immunomodulatory activity in macrophages during fungal infection.