In Vivo and in Vitro activity of colistin-conjugated bimetallic silver-copper oxide nanoparticles against Pandrug-resistant Pseudomonas aeruginosa.
Asmaa Abdul HakHamdallah H ZedanHadir A El-MahallawyGharieb S El-SayyadMai M ZaferPublished in: BMC microbiology (2024)
The synthesis of bimetallic Ag-CuO NPs conjugated with colistin presents a promising alternative treatment for combating the challenging P. aeruginosa pathogen in hospital settings. Further research is needed to explore and elucidate the mechanisms underlying the inhibitory effects of colistin-bimetallic Ag-CuO NPs on microbial persistence and dissemination.
Keyphrases
- oxide nanoparticles
- pseudomonas aeruginosa
- acinetobacter baumannii
- escherichia coli
- cystic fibrosis
- klebsiella pneumoniae
- biofilm formation
- multidrug resistant
- drug resistant
- gram negative
- metal organic framework
- quantum dots
- photodynamic therapy
- microbial community
- highly efficient
- combination therapy
- replacement therapy