Adverse Outcomes Associated With Interleukin-6 in Patients Recently Hospitalized for Heart Failure With Preserved Ejection Fraction.

Leanne MooneyColette E JacksonCarly Adamson Alexander McConnachie Paul I Welsh Rachel C Myles John Joseph Valentine McMurray Pardeep S Jhund Mark Colquhoun Petrie Ninian N Lang

Published in: Circulation. Heart failure (2023)

In patients recently hospitalized with heart failure with preserved ejection fraction, IL-6 is an independent predictor of all-cause mortality, cardiovascular death, and sHFH after adjustment for risk factors including BNP. These findings are of particular relevance in the context of current anti-IL-6 drug development.

Keyphrases

end stage renal disease
risk factors
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors