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Thymoquinone-induced antitumor and apoptosis in human lung adenocarcinoma cells.

Saeed SamarghandianMohsen Azimi-NezhadTahereh Farkhondeh
Published in: Journal of cellular physiology (2018)
Our results proposed that TQ may be a potential new therapeutic agent for the management of lung cancer. TQ promoted apoptosis in A546 lung cancer cells by the activation of p53 and caspase cascade dependent pathways.
Keyphrases
  • cell cycle arrest
  • cell death
  • induced apoptosis
  • endoplasmic reticulum stress
  • oxidative stress
  • pi k akt
  • endothelial cells
  • diabetic rats
  • high glucose
  • signaling pathway
  • drug induced
  • stress induced