Minimal Residual Disease Status Predicts Outcome in Patients With Previously Untreated Follicular Lymphoma: A Prospective Analysis of the Phase III GALLIUM Study.
Christiane PottVindi JurinovicJudith TrotmanBritta KehdenMichael UnterhaltMichael HeroldRichard van der JagtAnn JanssensMichael KnebaJiří MayerMoya YoungChristian SchmidtAndrea KnappTina NielsenHelen BrownNathalie SpielewoyChris HarbronAlessia BottosKirsten MundtRobert MarcusWolfgang HiddemannEva HosterPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
MRD status can determine outcome after induction and during maintenance, and MRD negativity is a prerequisite for long-term disease control in FL. The higher MRD responses after G- versus R-based treatment confirm more effective tumor cell clearance.