Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries.
Ju-Sheng ZhengStephen J SharpFumiaki ImamuraRajiv ChowdhuryThomas E GundersenMarinka SteurIvonne SluijsYvonne T van der SchouwAntonio AgudoDagfinn AuneAurelio BarricarteHeiner BoeingMaría-Dolores ChirlaqueMiren DorronsoroHeinz FreislingDouae El-FatouhiPaul W FranksGuy FagherazziSara GrioniMarc J GunterCecilie KyrøVerena KatzkeTilman KühnKay-Tee KhawNasser LaoualiGiovanna MasalaPeter M NilssonKim OvervadSalvatore PanicoKeren PapierJ Ramón QuirósOlov RolandssonDaniel Redondo-SánchezFulvio RicceriMatthias B SchulzeAnnemieke M W SpijkermanAnne TjønnelandTammy Y N TongRosario TuminoElisabete WeiderpassJohn DaneshAdam S ButterworthElio RiboliNita G ForouhiNicholas J WarehamPublished in: BMJ (Clinical research ed.) (2020)
These findings indicate an inverse association between plasma vitamin C, carotenoids, and their composite biomarker score, and incident type 2 diabetes in different European countries. These biomarkers are objective indicators of fruit and vegetable consumption, and suggest that diets rich in even modestly higher fruit and vegetable consumption could help to prevent development of type 2 diabetes.