Characteristics of the Gut Microbiota and Metabolism in Patients With Latent Autoimmune Diabetes in Adults: A Case-Control Study.

Yuanyuan FangChenhong ZhangHongcai ShiWei WeiJing ShangRuizhi ZhengLu YuPingping WangJunpeng YangXinru DengYun ZhangShasha TangXiaoyang ShiYalei LiuHuihui YangQian YuanRui ZhaiHuijuan Yuan

Published in: Diabetes care (2021)

The characteristic gut microbiota and related metabolites of patients with LADA are associated with autoantibodies, glucose metabolism, islet function, and inflammatory factors, which may contribute to the pathogenesis of LADA. Future longitudinal studies should explore whether modulating the gut microbiota and related metabolites can alter the natural course of autoimmune diabetes in the quest for new therapeutics.

Keyphrases

type diabetes
cardiovascular disease
ms ms
multiple sclerosis
glycemic control
systemic lupus erythematosus
signaling pathway
small molecule
oxidative stress
metabolic syndrome
skeletal muscle
adipose tissue