Evaluation safety and efficacy of immune checkpoint blockers (ICB) and radiotherapy combination versus ICB in non-small cell lung cancer patients with recurrence or metastasis: A systematic review and meta-analysis.

Yichun ZengLiying ZhangYichen LiangXian ZhangLei LiMaoqi WangJingliang GuoQiuxian LiJin CaoJuan J GuBu-Hai Wang

Published in: Cancer medicine (2023)

RT can significantly improve ORR, DCR, OS, and PFS of ICB in patients with recurrent or metastatic NSCLC without increasing toxicity. PD-1 inhibitor following SRS/SBRT could be the best option to maximally benefit the patients.

Keyphrases

small cell lung cancer
end stage renal disease
radiation therapy
ejection fraction
chronic kidney disease
newly diagnosed
early stage
squamous cell carcinoma
patient reported outcomes
radiation induced
angiotensin converting enzyme
rectal cancer
patient reported
angiotensin ii