Acquisition of paclitaxel resistance modulates the biological traits of gastric cancer AGS cells and facilitates epithelial to mesenchymal transition and angiogenesis.

Ali NiapourNaisana Seyedasli

Published in: Naunyn-Schmiedeberg's archives of pharmacology (2022)

AGS-R cells could bypass chemotherapy stress by expressing the genes coding for efflux pumps and altering some key signaling in favor of survival, EMT, and angiogenesis.

Keyphrases

induced apoptosis
cell cycle arrest
endothelial cells
genome wide
vascular endothelial growth factor
endoplasmic reticulum stress
squamous cell carcinoma
cell death
signaling pathway
radiation therapy
oxidative stress
dna methylation
heat stress