PHACTR1 modulates vascular compliance but not endothelial function: a translational study.
Alice WoodAlexios AntonopoulosSurawee ChuaiphichaiTheodosios KyriakouRebeca DiazAbtehale Al HussainiAnna-Marie MarshManjit SianMitul MeisuriaGerry P McCannVictoria S RashbrookEdward DrydaleSally DraycottMurray David PolkinghorneIoannis AkoumianakisCharalambos AntoniadesHugh C WatkinsKeith M ChannonDavid AdlamGillian DouglasPublished in: Cardiovascular research (2022)
In conclusion, we have shown a role for PHACTR1 in arterial compliance across multiple vascular beds. Our study suggests that PHACTR1 has a key structural role within the vasculature.
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