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Prenatal Lipopolysaccharides Exposure Induces Transgenerational Inheritance of Hypertension.

Nian CaoCong LanCaiyu ChenZaicheng XuHao LuoShuo ZhengXue GongHongmei RenZhuxin LiShuang QuCheng YuJining YangPedro A JoseYundai ChenGengze WuCuimei HuJunyi YuChunyu Zeng
Published in: Circulation (2022)
These findings show that adverse prenatal exposure induces transgenerational hypertension through an epigenetic-regulated mechanism and identify potentially preventive and therapeutic strategies for hypertension.
Keyphrases
  • blood pressure
  • pregnant women
  • dna methylation
  • gene expression
  • transcription factor
  • mitochondrial dna
  • arterial hypertension