Molecular analysis for ovarian cancer detection in patient-friendly samples.
Birgit M M WeverMirte SchaafsmaMaaike C G BleekerYara van den BurgtRianne van den HelderChristianne A R LokFrederike DijkYmke van der PolFlorent MouliereNorbert MoldovanNienke E van TrommelRenske D M SteenbergenPublished in: Communications medicine (2024)
Our study reveals increased methylation levels of ovarian cancer-associated genes and copy number aberrations in the urine of ovarian cancer patients. Our findings support continued research into urine biomarkers for ovarian cancer detection and highlight the importance of including benign ovarian masses in future studies to develop a clinically useful test.
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