Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study.
Takeshi SakuraTomoaki MoriokaAtsushi ShioiYoshinori KakutaniYuya MikiYuko YamazakiKoka MotoyamaKatsuhito MoriShinya FukumotoTetsuo ShojiMasanori EmotoMasaaki InabaPublished in: Cardiovascular diabetology (2017)
Serum LBP levels are associated with arterial stiffness, independent of obesity and traditional cardiovascular risk factors, especially in men with type 2 diabetes. This study indicates a potential role of the LPS/LBP-induced innate immunity in the development and progression of arterial stiffness in type 2 diabetes.
Keyphrases
- cardiovascular risk factors
- type diabetes
- blood pressure
- metabolic syndrome
- binding protein
- inflammatory response
- cardiovascular disease
- insulin resistance
- weight loss
- high glucose
- toll like receptor
- diabetic rats
- weight gain
- anti inflammatory
- risk factors
- risk assessment
- climate change
- immune response
- oxidative stress
- body mass index