A Rare Case of Undifferentiated Pleomorphic Cardiac Sarcoma with Inflammatory Pattern.
Alexandra Iulia StoicaMarius Mihai HarpaCosmin Marian BanceuClaudiu GhiragosianCarmen Elena OprisHussam Al-HusseinHamida Al-HusseinSanziana Flamind OlteanTibor MezeiRazvan Gheorghita MaresHoratiu SuciuPublished in: Medicina (Kaunas, Lithuania) (2022)
Cardiac undifferentiated pleomorphic sarcoma (UPS) associated with fever and inflammatory response is an extremely rare condition. Herein, we report a rare case of cardiac UPS with unusual clinical presentation and inflammatory response. A 67-year-old male complaining of progressive dyspnea and intermittent fever of unknown cause was referred to our hospital for surgical resection of a left atrial mass. Laboratory analysis showed leukocytosis (26 × 10 3 /μL) and high C-reactive protein (CRP) levels (155.4 mg/L). Hemoculture tests and urine analysis were negative for infection. A contrast chest computed tomography revealed a mass measuring 5.5 × 4.5 cm, occupying the left atrium cavity. The patient underwent surgical excision of the mass, however, surgical margin of the resected tumor could not be evaluated, due to the multifragmented nature of the resection specimen. Postoperative CRP and leukocyte levels normalized, highlighting the relationship between the tumor and the inflammatory status. Early diagnosis is crucial for a proper management and favorable outcome, enabling patients to undergo chemotherapy and achieve complete surgical resection.
Keyphrases
- rare case
- inflammatory response
- left ventricular
- left atrial
- computed tomography
- end stage renal disease
- ejection fraction
- mitral valve
- newly diagnosed
- multiple sclerosis
- lipopolysaccharide induced
- healthcare
- chronic kidney disease
- atrial fibrillation
- prognostic factors
- heart failure
- magnetic resonance
- toll like receptor
- emergency department
- squamous cell carcinoma
- locally advanced
- high intensity
- radiation therapy
- pulmonary hypertension
- inferior vena cava
- pulmonary embolism
- drug induced