Clonal Evolution of a High-Grade Pediatric Glioma With Distant Metastatic Spread.

Eliana MarinariValerie DutoitSergey NikolaevMaria Isabel VargasKarl SchallerJohannes Alexander LobrinusPierre-Yves DietrichPetros TsantoulisDenis Migliorini

Published in: Neurology. Genetics (2021)

Our findings demonstrate tumor spread outside the CNS and identify potential genetic drivers of metastatic dissemination outside the CNS, which could be leveraged as therapeutic targets or potential biomarkers.

Keyphrases

high grade
squamous cell carcinoma
small cell lung cancer
blood brain barrier
low grade
lymph node
genome wide
copy number
risk assessment
human health
dna methylation