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A wide scan of plasma proteins demonstrates thioredoxin reductase 1 as a potential new diagnostic biomarker for hepatocellular carcinoma.

Robin ZenlanderClaudia FredoliniJochen M SchwenkIngvar RydénPeter PåhlssonChristian LöwbeerGösta EggertsenPer Stål
Published in: Scandinavian journal of gastroenterology (2023)
In the present study, TXNRD1 improves the sensitivity and specificity of AFP and DCP as HCC screening tools in patients with cirrhosis. We suggest that TXNRD1 should be validated in prospective settings as a new complementary HCC biomarker together with AFP and DCP.
Keyphrases
  • risk assessment
  • human health