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Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.

Despoina ManousakiLavinia PaternosterMarie StandlMiriam F MoffattMartin FarrallEmmanuelle BouzigonDavid P StrachanFlorence DemenaisMark LathropWilliam O C M CooksonJohn Brent Richards
Published in: PLoS medicine (2017)
In this study, we found no evidence that genetically determined reduction in 25OHD levels conferred an increased risk of asthma, atopic dermatitis, or elevated total serum IgE, suggesting that efforts to increase vitamin D are unlikely to reduce risks of atopic disease.
Keyphrases
  • atopic dermatitis
  • chronic obstructive pulmonary disease
  • lung function
  • allergic rhinitis
  • human health