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Three residues in the BTB domain promote a good partnership between NuRD and Thpok.

Kazuki OkuyamaIchiro Taniuchi
Published in: Science immunology (2022)
Among the BTB-ZF transcription factor family, three amino acids in the BTB domain make Thpok unique in repressing cytotoxic lineage-related genes via recruitment of the NuRD chormatin-remodeling complex (see the related Research Article by Gao et al. ).
Keyphrases
  • transcription factor
  • amino acid
  • single cell
  • dna binding