Demographic, Medical, and Clinical Characteristics of a Population Based Sample of Patients With Long-lasting Locked-in Syndrome.

Investigating an unselected population-based sample of patients with vascular LIS offers important insights into LIS's functional diversity. Although most patients remained severely disabled, even small improvements in function can substantially increase the potential for activity and participation. Additional lesions outside the brain stem seem to be common in long-lasting LIS and might be prognostic for remaining in the LIS state.