Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: a survey study.
Lisa WaterinkLarissa A MasselinkSven J van der LeeLeonie N C VisserSolange CleutjensJetske van der SchaarArgonde C van HartenPhilip ScheltensSietske A M SikkesWiesje M van der FlierMarissa D ZwanPublished in: Alzheimer's research & therapy (2024)
Our findings indicate that the vast majority of CN adults participating in a research registry expresses interest in AD genetic risk research and disclosure. Interest in genetic risk disclosure is higher in scenarios corresponding to the APOE-ε4 genotype. This suggests APOE-ε4 screening within an online research registry is potentially a well-received method to accelerate inclusion for trials.