Comparative analysis of creatinine and osmolality as urine normalization strategies in targeted metabolomics for the differential diagnosis of asthma and COPD.

Mona M KhamisTeagan HoltHanan AwadAnas El-AneedDarryl J Adamko

Published in: Metabolomics : Official journal of the Metabolomic Society (2018)

Our findings suggest that targeted urine metabolomic data can be normalized for hydration using creatinine or osmolality with no significant impact on the diagnostic accuracy of the model.

Keyphrases

chronic obstructive pulmonary disease
lung function
cancer therapy
uric acid
electronic health record
big data
cystic fibrosis