Pre-pulse inhibition deficits in individuals at clinical high-risk for psychosis: A systematic review and meta-analysis.
Weidi LiZhen MaoQi-Jing BoYue SunZhimin WangChuanyue WangPublished in: Early intervention in psychiatry (2020)
CHR individuals had lower PPI level compared to HC in 120 ms paradigm, which were relatively stable and significant. The results indicate the presence of information processing and inhibitory problems prior to the development of full-blown psychosis. PPI may be clinically used as an objective indicator to supplement the understanding of CHR individuals.