Macrophage GSK3β-deficiency inhibits the progression of hepatocellular carcinoma and enhances the sensitivity of anti-PD1 immunotherapy.
Guangshun SunHanyuan LiuJie ZhaoJinyu ZhangTian HuangGuoqiang SunSiqi ZhaoZihao ZhangHengsong CaoDawei RongXiangyi KongQinghua JiLi LiuXuehao WangWeiwei TangYongxiang XiaPublished in: Journal for immunotherapy of cancer (2023)
in PBMC can noninvasively predict anti-PD1 sensitivity in HCC patients, which provides novel strategies to predict anti-PD1 sensitivity, increase anti-PD1 therapeutic effect, and bring new hope for HCC patients.