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Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism.

Lata KaphaliaMukund P SrinivasanRamu D KakumanuBhupendra S KaphaliaWilliam J Calhoun
Published in: Alcoholism, clinical and experimental research (2019)
EtOH-induced impaired phagocytosis, oxidative stress, ER stress, and dysregulated AMPK signaling are plausibly associated with the formation of FAEEs and may participate in the pathogenesis of nonspecific pulmonary inflammation.
Keyphrases
  • oxidative stress
  • diabetic rats
  • endothelial cells
  • skeletal muscle
  • high glucose
  • pulmonary hypertension
  • protein kinase
  • ischemia reperfusion injury
  • induced pluripotent stem cells