Deep serological profiling of the Trypanosoma cruzi TSSA antigen reveals different epitopes and modes of recognition by Chagas disease patients.
Guadalupe RomerLeonel A BraccoAlejandro D RicciVirginia BalouzLuisa BernáJuan C VillarJanine M RamseyMelissa S NolanFaustino TorricoNorival KesperJaime AltchehCarlos RobelloCarlos A BuscagliaFernán AgüeroPublished in: PLoS neglected tropical diseases (2023)
Overall, our findings shed new light into TSSA evolution, epitope landscape and modes of recognition by Chagas disease patients; and have practical implications for the design and/or evaluation of T. cruzi serotyping strategies.