Keratinocytes-Derived Reactive Oxygen Species Play an Active Role to Induce Type 2 Inflammation of the Skin: A Pathogenic Role of Reactive Oxygen Species at the Early Phase of Atopic Dermatitis.
Da-In ChoiJun-Hyeong ParkJee-Young ChoiMeiShan PiaoMin-Song SuhJee-Bum LeeSook-Jung YunSeung-Chul LeePublished in: Annals of dermatology (2020)
Our results reveal that keratinocytes-derived ROS, irrespective to their origins from allergens or non-allergens, have a potential to induce type 2 inflammation of AD skin.