Baseline characteristics of systemic lupus erythematosus patients included in the Lupus Italian Registry of the Italian Society for Rheumatology.
Gian Domenico SebastianiFrancesca Romana SpinelliElena BartoloniAlessandra BortoluzziEnrica BozzoloClaudia CanofariValentina CantiPaola ConigliaroMaria Chiara DittoGiacomo EmmiFranco FranceschiniMicol FrassiLuca IaccarinoAnnamaria IulianoAngelo ManfrediViviana PacucciSimone ParisiGiulia PazzolaRoberto PerriconeImmacolata PreveteGiuseppe Alvise RamirezSalvatore ScarpatoChiara SciroccoEttore SilvagniMargherita ZenAnna ZanettiGreta CarraraCarlo Alberto ScirèFabrizio ContiAndrea DoriaPublished in: Lupus (2021)
The predominant organ involvement was different in the two cohorts: kidney involvement predominated in NBC, joint involvement in BC. Despite the younger age at disease onset, patients of the BC had a longer disease duration and more frequently had taken a cumulative prednisone dosage greater than 10 g. Even the pattern of clinical manifestations inducing to prescribe biological rather than conventional immunosuppressants was quite different.Keywords: Autoantibody(ies), autoimmune disease, belimumab, cohort studies, glucocorticoids, immunosuppressants, rituximab, systemic lupus erythematosus.