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Lysosomal-Associated Protein Transmembrane 5, Tubular Senescence, and Progression of CKD.

Xiaohan LiuPing ZhanYang ZhangHuiying JinYouzhao WangYujie YangZiying WangXiaojie WangQianqian XuJunhui ZhenRong SunJinpeng SunMin LiuFan Yi
Published in: Journal of the American Society of Nephrology : JASN (2024)
LAPTM5 contributed to tubular senescence by regulating WWP2/NICD1 signaling pathway and exacerbated kidney injury during the progression of CKD.
Keyphrases
  • chronic kidney disease
  • signaling pathway
  • endothelial cells
  • dna damage
  • high glucose
  • stress induced
  • pi k akt
  • epithelial mesenchymal transition
  • cell proliferation