Unique Characteristics of Prepubertal Onset Systemic Lupus Erythematosus.
Reem AbdawaniE AbdallaIbrahim Al-ZakwaniPublished in: International journal of pediatrics (2019)
Distinct clinical features were identified in prepubertal onset pSLE population of Arab ethnicity. Given the high rate of consanguineous marriage and high frequency of familial SLE in this cohort, these manifestations could be explained by higher frequency of genetic factors that influence the disease pathogenesis.