Whole Transcriptome Sequencing of Peripheral Blood Identifies the Alzheimer's Disease-Related circRNA-miRNA-lncRNA Pathway.

Yucheng GuNihong ChenLin ZhuXiangliang ChenTeng JiangYingdong Zhang

Published in: Current neurovascular research (2024)

The study suggests that circRNAs may be independent of messenger RNAs (mRNAs) in AD pathogenesis and holds promise as potential biomarkers for AD clinical manifestations and pathological changes.

Keyphrases

peripheral blood
genome wide
single cell
gene expression
cognitive decline
long non coding rna
big data
deep learning
artificial intelligence
mild cognitive impairment