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Notch signaling pathway in infectious diseases: role in the regulation of immune response.

Ricardo Cardoso CastroRelber Aguiar GonçalesFabiana Albani ZambuziFabiani Gai Frantz
Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2021)
In this review, we present an overview of evidence that demonstrates the direct and indirect effects of interaction between the Notch signaling pathway and the immune responses against bacterial, viral, fungal, and parasitic infections, as well as the importance of this pathway to predict the outcome of infectious diseases.
Keyphrases
  • infectious diseases
  • immune response
  • signaling pathway
  • pi k akt
  • cell proliferation
  • epithelial mesenchymal transition
  • induced apoptosis
  • dendritic cells
  • toll like receptor
  • sars cov
  • endoplasmic reticulum stress