Inhibitory effect of purple rice husk extract on AFB1-induced micronucleus formation in rat liver through modulation of xenobiotic metabolizing enzymes.

Arpamas ChariyakornkulCharatda PunvittayagulSirinya TayaRawiwan Wongpoomchai

Published in: BMC complementary and alternative medicine (2019)

PRHE showed potent cancer chemopreventive activity in a rat liver micronucleus assay through modulation of phase I and II xenobiotic metabolizing enzymes involved in AFB1 metabolism. Vitamin E and phenolic compounds may be candidate antimutagens in purple rice husk.

Keyphrases

oxidative stress
diabetic rats
papillary thyroid
high glucose
anti inflammatory
high throughput
squamous cell
drug induced
squamous cell carcinoma
endothelial cells